SANTA CRUZ, Calif.--(EON: Enhanced Online News)--The University of California, Santa Cruz, has established a large-scale data repository and user portal for the National Cancer Institute's cancer genome research programs. The Cancer Genomics Hub (CGHub) is providing cancer researchers with efficient access to a large and rapidly growing store of valuable biomedical data to advance the field of "personalized" or "precision" care, in which doctors design treatments to target specific genetic changes found in a patient's cancer cells.
“By providing researchers with comprehensive catalogs of the key genomic changes in many major types and subtypes of cancer, these efforts will support the development of more effective ways to diagnose and treat cancer.”
The CGHub project is led by David Haussler, director of the Center for Biomolecular Science and Engineering at UC Santa Cruz, and funded by the National Cancer Institute (NCI) through a $10.3 million subcontract with SAIC-Frederick Inc., the prime contractor for the Frederick National Laboratory for Cancer Research.
Haussler's group built CGHub to support all three major NCI cancer genome sequencing programs, including The Cancer Genome Atlas (TCGA). These programs are laying the foundation for personalized cancer care by creating a database that scientists around the world can use to connect specific genomic changes with clinical outcomes. Haussler's group has been closely involved in data analysis for TCGA, which currently generates about 10 terabytes of data each month. There is an urgent need for an efficient and user-friendly portal to give researchers access to the data.
"The scale of this is far beyond anything faced in medical research before," Haussler said. "By providing researchers with comprehensive catalogs of the key genomic changes in many major types and subtypes of cancer, these efforts will support the development of more effective ways to diagnose and treat cancer."
Managed by the UCSC team, the CGHub computer system is located at the San Diego Supercomputer Center. It is connected by high-performance national research networks to major centers nationwide that are participating in these projects, including UCSC. Haussler's team designed and oversees the storage and computing infrastructure for the repository.
The CGHub project is 100 percent funded by the National Institutes of Health, in the amount of $10,300,000 using prime contract HHSN261200800001E, from the Frederick National Laboratory for Cancer Research.
For more information, see the full press release at: http://news.ucsc.edu/2012/05/cancer-genomics.html